Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | TPH1 | P17752 | 5/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14403597 | 0.84 | TPH1 (0.57) | HSD17B10ALOX15TDP1SLC7A5PTGS1 | |
| SCHEMBL25356472 | 0.82 | TPH1 (0.60) | HSD17B10SLC7A5PTGS1ALPIPKM | |
| SCHEMBL30722995 | 0.82 | TPH1 (0.60) | HSD17B10SLC7A5PTGS1ALPIPKM | |
| SCHEMBL25357127 | 0.82 | TPH1 (0.60) | HSD17B10SLC7A5PTGS1ALPIPKM | |
| SCHEMBL31303988 | 0.82 | TPH1 (0.60) | HSD17B10SLC7A5PTGS1ALPIPKM | |
| SCHEMBL25356476 | 0.82 | TPH1 (0.60) | HSD17B10SLC7A5PTGS1ALPIPKM | |
| SCHEMBL12273163 | 0.80 | SLC7A5 (0.54) | HSD17B10ALOX15TDP1SLC7A5PTGS1 | |
| SCHEMBL30673627 | 0.80 | SLC7A5 (0.54) | HSD17B10ALOX15TDP1SLC7A5PTGS1 | |
| SCHEMBL31295364 | 0.80 | SLC7A5 (0.54) | HSD17B10ALOX15TDP1SLC7A5PTGS1 | |
| SCHEMBL29462215 | 0.80 | SLC7A5 (0.54) | HSD17B10ALOX15TDP1SLC7A5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | HSD17B10 3828/4885ALOX15 4849/4885TDP1 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.