SCHEMBL31369923

SCHEMBL31369923

N#Cc1ccc(CC[C@H](N)C(=O)O)nc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.43
DPP7 Q9UHL4 1/20 0.42
TPH1 P17752 1/20 0.41
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40
GRM4 Q14833 1/20 0.40
NOS1 P29475 3/20 0.38
EP300 Q09472 1/20 0.37
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
PPARG P37231 1/20 0.36
ACACB O00763 1/20 0.36
MMP2 P08253 1/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6543229 0.79 GRM8 (0.41) GRIK1GRIK2GRM4NOS1
SCHEMBL6543232 0.79 GRM8 (0.41) GRIK1GRIK2GRM4NOS1
SCHEMBL7412848 0.77 MMP12 (0.56) FFAR1DPP7TPH1GRIK1GRIK2
SCHEMBL2884150 0.77 FFAR1 (0.68) FFAR1MMP2
SCHEMBL20582285 0.76 FFAR1 (0.50) FFAR1DPP7ACACBMMP2
SCHEMBL3927659 0.75 FFAR1 (0.56) FFAR1MMP2
SCHEMBL25179498 0.74 KMT2A (0.49) GRIK1GRIK2GRM4PPARG
SCHEMBL25179497 0.74 KMT2A (0.49) GRIK1GRIK2GRM4PPARG
SCHEMBL17501399 0.73 EGLN1 (0.47) FFAR1MMP2
SCHEMBL1769777 0.73 DPP7 (0.44) DPP7TPH1GRIK1GRIK2GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 FFAR1 3810/4885DPP7 428/4885TPH1 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.