SCHEMBL31369959

SCHEMBL31369959

N[C@@H](CCC(=O)Nc1cccc(F)c1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 10/20 0.66
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
FOLH1 Q04609 1/20 0.57
ALDH1A1 P00352 1/20 0.54
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
PRMT5 O14744 1/20 0.49
WDR77 Q9BQA1 1/20 0.49
POLB P06746 2/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23417761 0.84 LTA4H (0.68) LTA4HMAPT
SCHEMBL176813 0.84 LTA4H (0.91) LTA4HALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL2522620 0.84 LTA4H (0.91) LTA4HALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL177182 0.83 LTA4H (0.66) LTA4HMEN1KMT2AMAPT
SCHEMBL27981283 0.83 LTA4H (0.66) LTA4HMEN1KMT2AMAPT
SCHEMBL31369727 0.83 LTA4H (0.66) LTA4HMEN1KMT2AALDH1A1SLC1A3
SCHEMBL31369744 0.82 LTA4H (0.73) LTA4HMEN1KMT2AFOLH1ALDH1A1
SCHEMBL10076188 0.81 MAPT (0.65) LTA4HSLC1A2SLC1A1POLBMAPT
SCHEMBL6004419 0.80 CASR (0.66) LTA4H
SCHEMBL11613830 0.80 CASR (0.66) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 LTA4H 4516/4885MEN1 4354/4885KMT2A 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.