SCHEMBL31370160

SCHEMBL31370160

O=C(O)[C@@H]1CC[C@H](c2cccc3ccccc23)N1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 18/20 0.41
FABP7 O15540 2/20 0.41
FABP5 Q01469 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366299 0.88 FABP5 (0.51) FFAR2FABP7FABP5
SCHEMBL31159434 0.88 FABP5 (0.51) FFAR2FABP7FABP5
SCHEMBL799703 0.88 FABP5 (0.51) FFAR2FABP7FABP5
Fluoride SCHEMBL7821537 0.86 FABP5 (0.50) FFAR2FABP7FABP5
SCHEMBL31369524 0.84 FFAR2 (0.56) FFAR2FABP7FABP5
SCHEMBL31369486 0.83 ACE (0.47) FFAR2FABP7FABP5
SCHEMBL31369417 0.82 FFAR2 (0.44) FFAR2FABP7FABP5
SCHEMBL31370144 0.81 FABP5 (0.49) FFAR2FABP7FABP5
SCHEMBL8124433 0.80 FABP5 (0.49) FFAR2FABP7FABP5
SCHEMBL13259973 0.79 FABP5 (0.46) FFAR2FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 US disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP FFAR2 3057/4885FABP7 224/4885FABP5 229/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 FFAR2 3403/4885FABP7 508/4885FABP5 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.