SCHEMBL31369417

SCHEMBL31369417

Cc1cccc([C@H]2CC[C@@H](C(=O)O)N2C(=O)OCC2c3ccccc3-c3ccccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 15/20 0.44
FABP5 Q01469 2/20 0.44
FABP7 O15540 1/20 0.44
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL799703 0.89 FABP5 (0.51) FFAR2FABP5FABP7
SCHEMBL31159434 0.89 FABP5 (0.51) FFAR2FABP5FABP7
SCHEMBL3366299 0.89 FABP5 (0.51) FFAR2FABP5FABP7
SCHEMBL31369486 0.89 ACE (0.47) FFAR2FABP5FABP7
Fluoride SCHEMBL7821537 0.88 FABP5 (0.50) FFAR2FABP5FABP7
SCHEMBL31369524 0.84 FFAR2 (0.56) FFAR2FABP5FABP7
SCHEMBL31370144 0.83 FABP5 (0.49) FFAR2FABP5FABP7EPHX2
SCHEMBL13259973 0.83 FABP5 (0.46) FFAR2FABP5FABP7EPHX2
SCHEMBL31370160 0.82 FFAR2 (0.41) FFAR2FABP5FABP7
SCHEMBL31370488 0.79 ROCK2 (0.45) FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 FFAR2 3403/4885FABP5 424/4885FABP7 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.