SCHEMBL31370920

SCHEMBL31370920

CC(S)=Cc1cccc(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.50
CHRM5 P08912 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 1/20 0.47
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
CHAT P28329 1/20 0.44
GRIN2D O15399 2/20 0.43
GRIN3B O60391 2/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRIN2B Q13224 2/20 0.43
GRIN2C Q14957 2/20 0.43
GRIN3A Q8TCU5 2/20 0.43
RELA Q04206 1/20 0.43
AKR1C3 P42330 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14198038 0.83 FBP1 (0.53) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL11547520 0.77 GLO1 (0.57) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL19677096 0.77 FBP1 (0.47) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL2500243 0.76 AKR1C3 (0.63) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL2500244 0.76 AKR1C3 (0.63) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL29293786 0.76 ALDH1A1 (0.54) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL11538355 0.74 AKR1C3 (0.49) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL28277422 0.74 FBP1 (0.45) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL11538352 0.74 AKR1C3 (0.49) FBP1CHRM5CYP1A2CYP2C9KMT2A
SCHEMBL27556307 0.73 ALDH1A1 (0.54) FBP1CYP1A2CYP2C9KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354781-B Synthesis method of organic thioether compound 江南大学 2024-12-13 CN disclosed