SCHEMBL3137155

SCHEMBL3137155

FC(F)(F)c1cc([B-](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(C(F)(F)F)c1.Fc1ccc([S+](c2ccccc2)c2ccc(F)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
KIF11 P52732 2/20 0.35
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
P2RX1 P51575 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
CETP P11597 1/20 0.32
DHFR P00374 2/20 0.32
TP53 P04637 1/20 0.32
TACR1 P25103 4/20 0.32
NPY5R Q15761 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
NPBWR1 P48145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3130049 1.00 TDP1 (0.36) TDP1ALDH1A1TSHRKIF11NR3C1
SCHEMBL3244276 0.92 TSHR (0.41) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL3144568 0.90 KIF11 (0.46) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL3139294 0.90 KIF11 (0.46) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL3139818 0.86 NFE2L2 (0.39) TDP1ALDH1A1TSHRKIF11P2RX1
SCHEMBL3132670 0.86 NFE2L2 (0.39) TDP1ALDH1A1TSHRKIF11P2RX1
SCHEMBL3134861 0.86 CYP19A1 (0.35) TDP1ALDH1A1TSHRKIF11DHFR
SCHEMBL3130596 0.86 KIF11 (0.37) ALDH1A1TSHRKIF11P2RX1TACR1
SCHEMBL3134845 0.86 CYP19A1 (0.35) TDP1ALDH1A1TSHRKIF11DHFR
SCHEMBL6513245 0.86 TSHR (0.41) ALDH1A1TSHRKIF11P2RX1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 TDP1 2913/4885ALDH1A1 139/4885TSHR 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.