Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144568 | 0.95 | KIF11 (0.46) | TSHRALDH1A1KIF11P2RX1IDO1 | |
| SCHEMBL3139294 | 0.95 | KIF11 (0.46) | TSHRALDH1A1KIF11P2RX1IDO1 | |
| SCHEMBL6513245 | 0.93 | TSHR (0.41) | TSHRALDH1A1KIF11P2RX1IDO1 | |
| SCHEMBL3137155 | 0.92 | TDP1 (0.36) | TSHRALDH1A1KIF11P2RX1IDO1 | |
| SCHEMBL3130049 | 0.92 | TDP1 (0.36) | TSHRALDH1A1KIF11P2RX1IDO1 | |
| SCHEMBL3134861 | 0.91 | CYP19A1 (0.35) | TSHRALDH1A1KIF11MAPTHTT | |
| SCHEMBL3130596 | 0.91 | KIF11 (0.37) | TSHRALDH1A1KIF11P2RX1TACR1 | |
| SCHEMBL3139818 | 0.91 | NFE2L2 (0.39) | TSHRALDH1A1KIF11P2RX1IDO1 | |
| SCHEMBL3134845 | 0.91 | CYP19A1 (0.35) | TSHRALDH1A1KIF11MAPTHTT | |
| SCHEMBL3132670 | 0.91 | NFE2L2 (0.39) | TSHRALDH1A1KIF11P2RX1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583740-B1 | FLUOROARYLSULFONIUM PHOTOACID GENERATORS | STX APRILIS INC (US) | 2010-05-26 | — | — | EP | disclosed |
| US-20090182172-A1 | Fluoroarylsulfonium photoacid generators | STX APRILIS, INC. | 2009-07-16 | — | — | US | disclosed |
| EP-1583740-A2 | FLUOROARYLSULFONIUM PHOTOACID GENERATORS | Aprilis, Inc. (US) | 2005-10-12 | — | — | EP | disclosed |
| US-20050059543-A1 | Fluoroarylsulfonium photoacid generators | APRILIS (US) | 2005-03-17 | — | — | US | disclosed |
| WO-2004058699-A2 | FLUOROARYLSULFONIUM PHOTOACID GENERATORS | APRILIS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182172-A1 | Fluoroarylsulfonium photoacid generators | PFAS, PAG1, TST | TSHR 3755/4885ALDH1A1 1301/4885KIF11 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.