Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.81 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443328 | 1.00 | MAPK14 (0.81) | MAPK14AXLALDH1A1SMN1; SMN2CDK2 | |
| SCHEMBL2445182 | 0.95 | MAPK14 (0.73) | MAPK14AXLALDH1A1HTR2AHTR2C | |
| SCHEMBL31371595 | 0.92 | MAPK14 (0.72) | MAPK14AXLALDH1A1HTR2AHTR2C | |
| Arry-797 SCHEMBL29349798 | 0.90 | MAPK14 (1.00) | MAPK14ALDH1A1SMN1; SMN2CDK2CDK1 | |
| Arry-797 SCHEMBL222635 | 0.90 | MAPK14 (1.00) | MAPK14ALDH1A1SMN1; SMN2CDK2CDK1 | |
| Arry-797 SCHEMBL29351662 | 0.90 | MAPK14 (1.00) | MAPK14ALDH1A1SMN1; SMN2CDK2CDK1 | |
| Arry-797 SCHEMBL31046796 | 0.90 | MAPK14 (1.00) | MAPK14ALDH1A1SMN1; SMN2CDK2CDK1 | |
| SCHEMBL31371520 | 0.89 | MAPK14 (0.70) | MAPK14ALDH1A1HTR2CRAD52MCHR2 | |
| SCHEMBL2446702 | 0.87 | MAPK14 (0.62) | MAPK14AXLALDH1A1SMN1; SMN2CDK2 | |
| SCHEMBL2443317 | 0.87 | MAPK14 (0.63) | MAPK14ALDH1A1SMN1; SMN2MCHR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056518-A1 | 5,6-DISUBSTITUTED ALKYL 1H AND 2H-INDAZOLES AS DUAL BUTYRYLCHOLINESTERASE AND p38α MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY DISEASES | UNIVERZA V LJUBLJANI (SI) | 2025-03-20 | — | — | WO | claimed |
| WO-2025056518-A1 | 5,6-DISUBSTITUTED ALKYL 1H AND 2H-INDAZOLES AS DUAL BUTYRYLCHOLINESTERASE AND p38α MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY DISEASES | UNIVERZA V LJUBLJANI (SI) | 2025-03-20 | — | — | WO | disclosed |