Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | TET3 | O43151 | 7/20 | 0.39 |
| ▸ | FBXL19 | Q6PCT2 | 7/20 | 0.39 |
| ▸ | CXXC5 | Q7LFL8 | 7/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.39 |
| ▸ | CXXC4 | Q9H2H0 | 7/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 5/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228827 | 0.78 | CNR2 (0.38) | CNR2VNN1 | |
| SCHEMBL21236898 | 0.77 | CNR2 (0.37) | CNR2VNN1 | |
| SCHEMBL18069128 | 0.77 | SMN1; SMN2 (0.42) | KMT2ACNR2VNN1MAPK1 | |
| SCHEMBL24244520 | 0.74 | KMT2A (0.42) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL20849781 | 0.74 | TET3 (0.45) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL19910567 | 0.72 | PDK2 (0.37) | CNR2VNN1 | |
| SCHEMBL19910592 | 0.72 | OPRM1 (0.45) | CNR2VNN1 | |
| SCHEMBL24244455 | 0.72 | KMT2A (0.44) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL27896663 | 0.71 | RORC (0.41) | KMT2ACNR2VNN1 | |
| SCHEMBL4224125 | 0.70 | USP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034849-A1 | FUSED PYRIDAZINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |