Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069131 | 0.90 | OPRM1 (0.40) | OPRM1ALDH1A1CNR2PDK2CHRNB2 | |
| SCHEMBL16887627 | 0.89 | PDK2 (0.41) | OPRM1ALDH1A1PDK2CHRNB2CHRNA3 | |
| SCHEMBL15492372 | 0.85 | ALDH1A1 (0.52) | OPRM1ALDH1A1CNR2PDK2CHRNB2 | |
| SCHEMBL18069128 | 0.80 | SMN1; SMN2 (0.42) | OPRM1ALDH1A1CNR2PDK2VNN1 | |
| SCHEMBL4228827 | 0.78 | CNR2 (0.38) | CNR2VNN1TRPA1RORC | |
| SCHEMBL23482193 | 0.78 | L3MBTL1 (0.40) | OPRM1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL21236898 | 0.77 | CNR2 (0.37) | CNR2VNN1RORC | |
| SCHEMBL18799681 | 0.76 | L3MBTL1 (0.41) | OPRM1ALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL19910567 | 0.76 | PDK2 (0.37) | CNR2PDK2CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL13246058 | 0.74 | ALDH1A1 (0.52) | OPRM1ALDH1A1CNR2CHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766860-B2 | Lysyl oxidase-like 2 inhibitors and uses thereof | PHARMAKEA, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20180057458-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766860-B2 | Lysyl oxidase-like 2 inhibitors and uses thereof | LOXL2, LOXL1, LOX | OPRM1 2363/4885ALDH1A1 982/4885CNR2 1446/4885 |
| US-20180057458-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | OPRM1 2363/4885ALDH1A1 982/4885CNR2 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.