Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31488176 | 0.84 | CFTR (0.35) | CNR2DGAT1 | |
| SCHEMBL4228827 | 0.82 | CNR2 (0.38) | CNR2VNN1RORC | |
| SCHEMBL18069128 | 0.81 | SMN1; SMN2 (0.42) | CNR2VNN1RORC | |
| SCHEMBL19910567 | 0.77 | PDK2 (0.37) | CNR2VNN1RORC | |
| SCHEMBL31371625 | 0.77 | KMT2A (0.39) | CNR2VNN1 | |
| SCHEMBL19910592 | 0.77 | OPRM1 (0.45) | CNR2VNN1RORC | |
| SCHEMBL29626659 | 0.76 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL27896663 | 0.75 | RORC (0.41) | CNR2VNN1RORC | |
| SCHEMBL4224125 | 0.74 | USP2 (0.44) | RORC | |
| SCHEMBL3869090 | 0.74 | VNN1 (0.38) | CNR2VNN1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265445-B1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| WO-2019149658-A1 | PYRAZOLE- AND INDAZOLE-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-08-08 | — | — | WO | disclosed |