SCHEMBL31373249

SCHEMBL31373249

NC(=O)c1cc(I)ccc1I

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2K2 P36507 5/20 0.41
MAP2K1 Q02750 5/20 0.41
PARP1 P09874 1/20 0.39
PTPRC P08575 1/20 0.39
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPRA P18433 1/20 0.39
PTPRB P23467 1/20 0.39
PTPRE P23469 1/20 0.39
PTPN6 P29350 1/20 0.39
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK8 P45983 1/20 0.36
DGAT1 O75907 1/20 0.35
NQO2 P16083 1/20 0.35
TPMT P51580 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3553379 0.80 MAPT (0.49) PARP1PTPN1ALDH1A1MAPTKDM4E
SCHEMBL688910 0.80 IKBKB (0.53) MAP2K2MAP2K1PTPRCPTPN2PTPN1
SCHEMBL1277864 0.79 PTPRC (0.53) MAP2K2MAP2K1PTPRCPTPN2PTPN1
SCHEMBL8282570 0.78 ERN1 (0.42) MAP2K2MAP2K1PARP1PTPRCPTPN2
SCHEMBL1786179 0.78 ALDH1A1 (0.50) MAP2K2MAP2K1ALDH1A1MAPTKDM4E
SCHEMBL1804347 0.78 KEAP1 (0.47) MAP2K2MAP2K1PARP1ALDH1A1MAPK8
SCHEMBL4174657 0.78 PARP1 (0.44) MAP2K2MAP2K1PARP1ALDH1A1MAPT
SCHEMBL1477485 0.78 MAP2K1 (0.54) MAP2K2MAP2K1PTPRCPTPN2PTPN1
SCHEMBL3166835 0.78 DGAT1 (0.55) PARP1PTPN2PTPN1PTPN6ALDH1A1
SCHEMBL24195885 0.77 PTPRC (0.39) MAP2K1PTPRCPTPN2PTPN1PTPRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250128220-A1 SYSTEMS WITH IMPROVED HYDROGEL FORMATION TIMES BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-04-24 US disclosed
WO-2025085642-A1 SYSTEMS WITH IMPROVED HYDROGEL FORMATION TIMES BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-04-24 WO disclosed
CN-119185628-A Self-developing liquid-carried medicine embolic agent and preparation method and application thereof 科睿驰(深圳)医疗科技发展有限公司 2024-12-27 CN disclosed