Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | YWHAG | P61981 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596944 | 0.83 | KDM4E (0.61) | MAPTKDM4EMEN1KMT2ATHRB | |
| SCHEMBL19971999 | 0.81 | MAPT (0.44) | MAPTKDM4EMEN1KMT2ATHRB | |
| SCHEMBL31373249 | 0.80 | MAP2K2 (0.41) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL1803658 | 0.79 | MAPT (0.53) | MAPTKDM4EMEN1KMT2ATHRB | |
| SCHEMBL1708814 | 0.77 | KMT2A (0.65) | MAPTKDM4EMEN1KMT2ATHRB | |
| SCHEMBL4174657 | 0.77 | PARP1 (0.44) | MAPTKDM4EMEN1KMT2AGFER | |
| SCHEMBL3166835 | 0.77 | DGAT1 (0.55) | MAPTKDM4EMEN1KMT2AALOX15 | |
| SCHEMBL1804347 | 0.77 | KEAP1 (0.47) | MEN1KMT2AALDH1A1TDP1PARP1 | |
| SCHEMBL31017519 | 0.76 | GAA (0.61) | MAPTKDM4EMEN1KMT2ATHRB | |
| SCHEMBL17375016 | 0.76 | GAA (0.61) | MAPTKDM4EMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718665-B | Insecticide for agricultural or horticultural use prepare intermediate | MITSUI CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-09-16 | — | — | CN | disclosed |
| CN-104892431-A | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS INC | 2015-09-09 | — | — | CN | disclosed |
| CN-102976984-B | Preparation intermediate of insecticide for agricultural and horticultural uses | MITSUI CHEMICALS INC | 2015-04-08 | — | — | CN | disclosed |
| US-7776922-B2 | Substituted [(phenylethanoyl)amino]benzamides | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776922-B2 | Substituted [(phenylethanoyl)amino]benzamides | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776922-B2 | Substituted [(phenylethanoyl)amino]benzamides | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20080171786-A1 | e.g. 2-(1-Benzothien-2-yl)-5-[(2-phenylbutanoyl)amino]benzamide; interleukin-8 receptor antagonist; antiinflammatory agent, cardiovascular diseases; arteriosclerosis, coronary heart disease, dyslipidemias, myocardial infarction, stroke, restenosis, reperfusion injury, thrombosis, ischemia | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171786-A1 | e.g. 2-(1-Benzothien-2-yl)-5-[(2-phenylbutanoyl)amino]benzamide; interleukin-8 receptor antagonist; antiinflammatory agent, cardiovascular diseases; arteriosclerosis, coronary heart disease, dyslipidemias, myocardial infarction, stroke, restenosis, reperfusion injury, thrombosis, ischemia | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171786-A1 | e.g. 2-(1-Benzothien-2-yl)-5-[(2-phenylbutanoyl)amino]benzamide; interleukin-8 receptor antagonist; antiinflammatory agent, cardiovascular diseases; arteriosclerosis, coronary heart disease, dyslipidemias, myocardial infarction, stroke, restenosis, reperfusion injury, thrombosis, ischemia | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | US | disclosed |
| EP-1814872-A1 | SUBSTITUTED [(PHENYLETHANOYL)AMINO] BENZAMIDES AND THE USE THEREOF IN THE TREATMENT OF INFLAMMATORY AND CARDIO-VASCULAR DISEASES | Bayer HealthCare AG (DE) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006053748-A1 | SUBSTITUTED [(PHENYLETHANOYL)AMINO] BENZAMIDES AND THE USE THEREOF IN THE TREATMENT OF INFLAMMATORY AND CARDIO-VASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171786-A1 | e.g. 2-(1-Benzothien-2-yl)-5-[(2-phenylbutanoyl)amino]benzamide; interleukin-8 receptor antagonist; antiinflammatory agent, cardiovascular diseases; arteriosclerosis, coronary heart disease, dyslipidemias, myocardial infarction, stroke, restenosis, reperfusion injury, thrombosis, ischemia | CXCL8, CASP8, TLR8 | MAPT 4296/4885KDM4E 2435/4885MEN1 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.