Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375610 | 0.78 | NPC1 (0.51) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28320114 | 0.78 | RAB9A (0.55) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4437276 | 0.71 | EPHX2 (0.48) | EPHX2ALDH1A1HPGDFAAHRAB9A | |
| SCHEMBL18795958 | 0.71 | HDAC6 (0.60) | HDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL17067047 | 0.71 | NOTUM (0.40) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL411970 | 0.70 | KDM4E (0.34) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31375482 | 0.69 | LOXL2 (0.49) | PDPK1CYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL2306778 | 0.68 | NOTUM (0.57) | EPHX2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28919968 | 0.68 | NPC1 (0.48) | ALDH1A1HPGDRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL15730396 | 0.68 | RAB9A (0.49) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |