Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103221 | 0.85 | ALDH1A1 (1.00) | GAAALDH1A1TDP1LMNAHDAC1 | |
| SCHEMBL5112618 | 0.83 | LMNA (0.54) | GAAALDH1A1LMNAHDAC6HTT | |
| SCHEMBL10591754 | 0.83 | POLB (0.71) | GAAALDH1A1TDP1LMNAHTT | |
| SCHEMBL29555730 | 0.83 | GAA (0.70) | GAAALDH1A1TDP1HDAC1HDAC6 | |
| SCHEMBL5122776 | 0.83 | POLB (0.56) | GAAALDH1A1TDP1LMNAHDAC1 | |
| SCHEMBL5539975 | 0.82 | LMNA (0.72) | GAAALDH1A1LMNAHDAC1HDAC6 | |
| SCHEMBL14604840 | 0.80 | GAA (0.48) | GAAALDH1A1TDP1LMNAHTT | |
| SCHEMBL2998715 | 0.79 | LMNA (0.71) | GAAALDH1A1LMNAHDAC1SMN1; SMN2 | |
| SCHEMBL8167142 | 0.78 | ALDH1A1 (0.69) | GAAALDH1A1TDP1HDAC1HDAC6 | |
| SCHEMBL13427112 | 0.78 | ALDH1A1 (0.83) | GAAALDH1A1TDP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |