Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375627 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL28455141 | 0.71 | NNMT (0.44) | NNMTHPGDSSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL30801504 | 0.65 | HDAC1 (0.68) | NNMTHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL669121 | 0.63 | NNMT (0.52) | NNMTHPGDSSMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL3407188 | 0.62 | NNMT (0.56) | NNMTSMN1; SMN2HDAC1HDAC6MKNK1 | |
| SCHEMBL17005755 | 0.62 | HDAC3 (0.49) | NNMTSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL30801502 | 0.62 | HDAC1 (0.64) | NNMTHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL20547577 | 0.62 | — | — | |
| SCHEMBL2715514 | 0.61 | NNMT (0.58) | NNMTHPGDSSMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL1745778 | 0.59 | NNMT (0.52) | NNMTSMN1; SMN2MKNK1MKNK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486992-A | PI3K alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-02-18 | — | — | CN | disclosed |