SCHEMBL31377299

SCHEMBL31377299

CC(=O)O[C@H]1[C@@H](Cc2ccc(OC(F)(F)F)cc2)N(C(=O)OC(C)(C)C)C[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABHD6 Q9BV23 2/20 0.41
▸ DAGLA Q9Y4D2 1/20 0.41
▸ RORC P51449 2/20 0.40
▸ LIPE Q05469 1/20 0.39
▸ KCNH2 Q12809 2/20 0.39
▸ SCN5A Q14524 2/20 0.39
▸ SCN9A Q15858 2/20 0.39
▸ CYP2D6 P10635 3/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SLC2A1 P11166 1/20 0.39
▸ GPR119 Q8TDV5 1/20 0.38
▸ EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31377297 0.89 SMN1; SMN2 (0.51) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA
SCHEMBL31377403 0.87 RORC (0.41) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA
SCHEMBL31421217 0.87 ABHD6 (0.40) ABHD6DAGLALIPEKCNH2SCN5A
SCHEMBL31377105 0.86 CYP2D6 (0.38) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA
SCHEMBL31421470 0.86 GPR119 (0.40) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA
SCHEMBL31377217 0.85 RORC (0.38) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA
SCHEMBL31377193 0.85 VEGFA (0.38) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA
SCHEMBL31377211 0.85 NR1H2 (0.45) —
SCHEMBL31377178 0.85 NR1H2 (0.45) —
SCHEMBL31421313 0.85 CYP2D6 (0.39) RORCCYP2D6SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ABHD6 2017/4885DAGLA 3713/4885RORC 2401/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ABHD6 2191/4885DAGLA 3737/4885RORC 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback