SCHEMBL3137764

SCHEMBL3137764

CCCCC(=O)NNS(=O)(=O)c1cccc2cccnc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.54
TSHR P16473 2/20 0.54
ALOX15 P16050 1/20 0.54
GAA P10253 3/20 0.51
ALDH1A1 P00352 3/20 0.51
POLB P06746 1/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
KDM4E B2RXH2 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
APOBEC3G Q9HC16 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PPARG P37231 1/20 0.48
FABP1 P07148 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 1/20 0.46
NPC1 O15118 1/20 0.46
HSP90AA1 P07900 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14313616 0.77 ALOX15 (0.74) TRPV1TSHRALOX15GAAALDH1A1
SCHEMBL28254889 0.76 GAA (0.64) TSHRALOX15GAAALDH1A1HTT
SCHEMBL9239543 0.75 ALOX15 (0.71) TRPV1TSHRALOX15ALDH1A1POLB
SCHEMBL28601651 0.75 HTT (0.76) TSHRGAAALDH1A1POLBMAPT
SCHEMBL13949767 0.74 POLB (0.68) TSHRALOX15GAAALDH1A1POLB
SCHEMBL14676752 0.73 GAA (0.51) TRPV1TSHRALOX15GAAALDH1A1
SCHEMBL10763531 0.72 MAPT (0.55) ALDH1A1POLBMAPTHTTKDM4E
SCHEMBL7318545 0.72 POLB (0.55) TRPV1TSHRALOX15GAAALDH1A1
SCHEMBL12000927 0.72 GAA (0.64) GAAALDH1A1POLBMAPTHTT
SCHEMBL4178176 0.72 MAPT (0.62) GAAALDH1A1POLBMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 TRPV1 968/4885TSHR 35/4885ALOX15 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.