Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601651 | 0.77 | HTT (0.76) | MAPTTDP1KMT2AALDH1A1HTT | |
| SCHEMBL10752030 | 0.75 | LMNA (0.55) | MAPTHSP90AA1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL1121857 | 0.75 | LMNA (0.55) | MAPTHSP90AA1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL8822078 | 0.75 | LMNA (0.55) | MAPTHSP90AA1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL5310788 | 0.75 | HSP90AA1 (0.64) | MAPTRAB9AHSP90AA1NPC1KDM4E | |
| SCHEMBL9257516 | 0.74 | HSP90AA1 (0.57) | MAPTHSP90AA1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL2484185 | 0.74 | MAPT (0.68) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL10751742 | 0.74 | LMNA (0.60) | MAPTRAB9AHSP90AA1KDM4EMAPK1 | |
| SCHEMBL8352456 | 0.73 | MEN1 (0.46) | MAPTRAB9AHSP90AA1NPC1KDM4E | |
| SCHEMBL9568616 | 0.73 | MAPT (0.66) | MAPTRAB9ANPC1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248399-A1 | Aminoazole derivatives and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-12-09 | — | — | EP | claimed |