Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.70 |
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.70 |
| ▸ | CASP3 | P42574 | 3/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | TP53 | P04637 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.70 |
| ▸ | RELA | Q04206 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401206 | 0.88 | RAB9A (0.79) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL29858577 | 0.88 | RAB9A (0.79) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL22103734 | 0.83 | NPC1 (0.81) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL29362501 | 0.83 | SMN1; SMN2 (1.00) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL152658 | 0.83 | SMN1; SMN2 (1.00) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL30153418 | 0.82 | RAB9A (1.00) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL2492958 | 0.82 | RAB9A (1.00) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL27672723 | 0.82 | RAB9A (0.70) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL27652504 | 0.82 | KDM4E (0.70) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL2490685 | 0.82 | NPC1 (1.00) | RAB9AKDM4ENPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674145-B | The preparation method of 2- aryl benzoxazoles, 2- aryl benzothiazole compound | 复旦大学 | 2019-11-12 | — | — | CN | disclosed |
| US-20100004301-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-07 | — | — | US | disclosed |
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
| EP-2102177-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| EP-1933834-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2008071944-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| WO-2007042816-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004301-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | RAB9A 3680/4885KDM4E 1264/4885NPC1 4501/4885 |
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | RAB9A 3680/4885KDM4E 1264/4885NPC1 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.