SCHEMBL31379547

SCHEMBL31379547

Fc1cc(Cl)cc(OCc2cscn2)c1Br

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.35
EPHA2 P29317 1/20 0.35
KDR P35968 1/20 0.35
EPHB4 P54760 1/20 0.35
GRM5 P41594 1/20 0.34
NMT1 P30419 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
SLC6A3 Q01959 1/20 0.32
EGFR P00533 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
MAPK14 Q16539 1/20 0.31
SCN1A P35498 1/20 0.31
SCN5A Q14524 1/20 0.31
SCN8A Q9UQD0 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23516857 0.80 MRGPRX4 (0.47) FLT1EPHA2KDREPHB4GRM5
SCHEMBL31379494 0.73 FLT1 (0.38) FLT1EPHA2KDREPHB4GRM5
SCHEMBL9873609 0.72 FLT1 (0.38) FLT1EPHA2KDREPHB4GRM5
SCHEMBL31379676 0.72 NOS3 (0.39) FLT1EPHA2KDREPHB4GRM5
SCHEMBL27192266 0.71 EGFR (0.40) FLT1EPHA2KDREPHB4GRM5
SCHEMBL31379484 0.71 GRM5 (0.45) FLT1EPHA2KDREPHB4GRM5
SCHEMBL31379678 0.70 FLT1 (0.38) FLT1EPHA2KDREPHB4GRM5
SCHEMBL27950179 0.70 L3MBTL1 (0.44) GRM5SLC6A3ALDH1A1HPGDHTT
SCHEMBL27301161 0.69 NOS3 (0.41) FLT1EPHA2KDREPHB4NOS3
SCHEMBL25213617 0.68 PLAU (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025036241-A1 COMPOUNDS AND METHODS FOR MODULATING RNA SPLICING RIBOPEUTIC INC. (CN) 2025-02-20 WO disclosed