Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669124 | 0.76 | ADRA2A (0.34) | KMT2A | |
| SCHEMBL647119 | 0.75 | ELANE (0.39) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL9076071 | 0.71 | ELANE (0.36) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL3135527 | 0.69 | DAO (0.41) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL17708233 | 0.69 | ALDH1A1 (0.42) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL9627001 | 0.68 | ELANE (0.46) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL17842623 | 0.67 | POLB (0.42) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL3192492 | 0.66 | POLB (0.53) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL13134171 | 0.64 | KDM4E (0.36) | ELANEALDH1A1KMT2AATM | |
| SCHEMBL15388582 | 0.64 | POLB (0.41) | ELANEALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139878-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |