Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | IL1RN | P18510 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31380346 | 0.80 | IRAK4 (0.35) | IRAK4HRH2HRH3 | |
| SCHEMBL4245388 | 0.80 | HRH4 (0.37) | IRAK4 | |
| SCHEMBL4073537 | 0.74 | ACHE (0.35) | IRAK4 | |
| SCHEMBL3311297 | 0.73 | IRAK4 (0.46) | IRAK4HRH2HRH3MEN1RAB9A | |
| SCHEMBL31380323 | 0.73 | LTA4H (0.37) | IRAK4HRH3 | |
| SCHEMBL31380415 | 0.72 | BACE1 (0.40) | IRAK4 | |
| SCHEMBL31380311 | 0.72 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL3858516 | 0.72 | CTSK (0.34) | IRAK4 | |
| SCHEMBL31380312 | 0.71 | MBOAT4 (0.33) | IRAK4RAB9A | |
| SCHEMBL31380305 | 0.70 | HDAC1 (0.48) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707931-A | Intermediate and synthesis method of 1- (1-oxo-1, 2-dihydro-phthalazin-6-yl) cycloalkyl-1-carboxamide derivatives as MTA synergistic inhibitors of PRMT5 | 百济神州(北京)生物科技有限公司 | 2025-03-28 | — | — | CN | disclosed |