Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31380372 | 0.87 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL31380346 | 0.77 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL31380312 | 0.70 | MBOAT4 (0.33) | IRAK4 | |
| SCHEMBL31380354 | 0.70 | CYP11B1 (0.38) | IRAK4CYP11B1CYP11B2ABL1 | |
| SCHEMBL31380397 | 0.69 | CYP11B2 (0.36) | IRAK4CYP11B2ABL1ALOX5AP | |
| SCHEMBL31380316 | 0.69 | HDAC1 (0.43) | — | |
| SCHEMBL17680262 | 0.68 | ALOX5AP (0.41) | ALOX5APFEN1 | |
| SCHEMBL31380323 | 0.67 | LTA4H (0.37) | IRAK4 | |
| SCHEMBL31380313 | 0.64 | HDAC1 (0.41) | ABL1 | |
| SCHEMBL30983305 | 0.64 | CHEK1 (0.42) | ABL1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707931-A | Intermediate and synthesis method of 1- (1-oxo-1, 2-dihydro-phthalazin-6-yl) cycloalkyl-1-carboxamide derivatives as MTA synergistic inhibitors of PRMT5 | 百济神州(北京)生物科技有限公司 | 2025-03-28 | — | — | CN | disclosed |