SCHEMBL31380892

SCHEMBL31380892

COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(C)c(C(F)(F)F)c(C=O)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.36
PIK3R2 O00459 1/20 0.36
PIK3CG P48736 1/20 0.36
QPCT Q16769 2/20 0.36
FABP4 P15090 3/20 0.36
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
DRD1 P21728 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21734048 0.82 PIK3CD (0.42) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL29384926 0.82 LMNA (0.37) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL31196081 0.82 PIK3CA (0.37) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL21733449 0.82 LMNA (0.37) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL30142533 0.81 TSPO (0.39) MAPTMEN1ALDH1A1KMT2ATSPO
SCHEMBL25339260 0.79 LMNA (0.34) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL26895501 0.78 ALDH1A1 (0.35) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL26694566 0.78 APLNR (0.40) PIK3CDPIK3R2PIK3CGFABP4MAPT
SCHEMBL26694426 0.78 ALDH1A1 (0.36) PIK3CDPIK3R2PIK3CGQPCTFABP4
SCHEMBL31057543 0.77 ALDH1A1 (0.39) QPCTLMNAMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026903-A1 IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2025-02-06 WO disclosed