SCHEMBL313823

SCHEMBL313823

[CH]1c2ccccc2-c2cccc(C3C=Cc4ccccc43)c21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32
CYP2D6 P10635 1/20 0.31
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15610196 0.87
SCHEMBL29386036 0.79 HTR2A (0.39) HTR6HTR2ACYP2D6SIGMAR1
SCHEMBL19630560 0.79 HTR2A (0.39) HTR6HTR2ACYP2D6SIGMAR1
Hydrochloric Acid SCHEMBL30769631 0.76 HTR2A (0.36) HTR6HTR2ACYP2D6SIGMAR1
Hydrochloric Acid SCHEMBL30769837 0.76 HTR2A (0.36) HTR6HTR2ACYP2D6SIGMAR1
Hydrochloric Acid SCHEMBL30769736 0.76 HTR2A (0.36) HTR6HTR2ACYP2D6SIGMAR1
SCHEMBL313501 0.74 HTR2A (0.38) HTR2A
SCHEMBL9288597 0.74
SCHEMBL8906322 0.73 SIGMAR1 (0.31) HTR6HTR2ACYP2D6SIGMAR1
SCHEMBL30388070 0.73 BRD4 (0.35) HTR6HTR2ACYP2D6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-106795348-B Thermoplastic polyolefins containing amorphous ethylene elastomers 埃克森美孚化学专利公司 2020-09-15 CN disclosed
US-20200239677-A1 Thermoplastic Polyolefin Containing Amorphous Ethylene Elastomer EXXONMOBIL CHEMICAL PATENTS INC. 2020-07-30 US disclosed
US-10647841-B2 Thermoplastic polyolefin containing amorphous ethylene elastomer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-05-12 US disclosed
US-10364308-B2 Thermoplastic polyolefin compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-07-30 US disclosed
US-10351647-B2 Polymerization process using bridged metallocene compounds supported on organoaluminum treated layered silicate supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-07-16 US disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
EP-2935297-B1 BRIDGED METALLOCENE COMPOUNDS, CATALYST SYSTEMS AND PROCESSES FOR POLYMERIZATION THEREWITH EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-03-20 EP disclosed
US-20180298127-A1 Polymerization Process Using Bridged Metallocene Compounds Supported on Organoaluminum Treated Layered Silicate Supports EXXONMOBIL CHEMICAL PATENTS INC. 2018-10-18 US disclosed
US-10087268-B2 Catalysts for the formation of multimodal polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-10-02 US disclosed
WO-2007022244-A2 PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS FINA TECHNOLOGY, INC. (US) 2007-02-22 WO disclosed
WO-2006137818-A1 CATALYST COMPONENTS AND THEIR USE IN THE POLYMERIZATION OF OLEFINS FINA TECHNOLOGY, INC. (US) 2006-12-28 WO disclosed
WO-2006012321-A2 IMPROVED ACIDIC ACTIVATOR-SUPPORTS AND CATALYSTS FOR OLEFIN POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-02-02 WO disclosed
US-20050288178-A1 Acidic activator-supports and catalysts for olefin polymerization CHEVRON PHILLIPS CHEMICAL COMPANY 2005-12-29 US disclosed
US-20050148460-A1 Catalyst components and their use in the polymerization of olefins FINA TECHNOLOGY, INC. 2005-07-07 US disclosed
EP-1064323-B1 METHOD OF PREPARING POLYOLEFIN NANOCOMPOSITES DOW GLOBAL TECHNOLOGIES INC (US) 2005-03-02 EP disclosed
US-6465543-B1 SWELLING HYDROPHILIC CLAY IN WATER, FREEZE DRYING AND CON-TACTING WITH AN ALKYL ALUMINOXANE TO FORM COMPLEX CATALYST AND PARTICLES; IN SITU OLEFIN OR STYRENIC POLYMERIZATION AND PLATELET DISPERSION; STRESS RESISTANT MOLDED PARTS THE DOW CHEMICAL COMPANY 2002-10-15 US disclosed
CN-1293692-A Polyolefin nanocomposites DOW CHEMIAL CO (US) 2001-05-02 CN disclosed
EP-1064323-A1 POLYOLEFIN NANOCOMPOSITES THE DOW CHEMICAL COMPANY (US) 2001-01-03 EP disclosed
WO-1999047598-A1 POLYOLEFIN NANOCOMPOSITES THE DOW CHEMICAL COMPANY (US) 1999-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148460-A1 Catalyst components and their use in the polymerization of olefins NPY5R, SSTR5, FGR HTR6 1247/4885HTR2A 621/4885CYP2D6 447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.