Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28903741 | 0.76 | HTR2A (0.38) | HTR2AGPR3ALDH1A1L3MBTL1CA1 | |
| SCHEMBL9322592 | 0.76 | PTGS2 (0.36) | — | |
| SCHEMBL3443208 | 0.75 | ALDH1A1 (0.37) | HTR2AALDH1A1 | |
| SCHEMBL2968887 | 0.74 | PTGS2 (0.41) | ALDH1A1 | |
| SCHEMBL313823 | 0.74 | HTR6 (0.32) | HTR2A | |
| SCHEMBL3192100 | 0.74 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL4022049 | 0.69 | HTR2A (0.46) | HTR2AGPR3ALDH1A1L3MBTL1CA1 | |
| SCHEMBL3630933 | 0.69 | ALDH1A1 (0.52) | HTR2AGPR3ALDH1A1L3MBTL1CA1 | |
| SCHEMBL246576 | 0.68 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1CA1CA2 | |
| SCHEMBL216981 | 0.68 | ACHE (0.39) | ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| EP-1915401-A2 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2008-04-30 | — | — | EP | disclosed |
| US-7335711-B2 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-20080026935-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2007022244-A2 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| CN-1079406-C | Mesoscopic organopolysiloxane particles with chemically bonded metal compounds | WACKER CHEMIE GMBH (DE) | 2002-02-20 | — | — | CN | disclosed |
| US-6008309-A | CROSSLINKED ORGANOPOLYSILOXANE PARTICLES OF UNIFORM PARTICLE SIZE DISTRIBUTION HAVING CHEMICALLY BONDED METALS, SOLUBLE IN ORGANIC SOLVENTS SUCH AS METHYLENE CHLORIDE, PENTANE, ACETONE, ETHANOL AND WATER; USE IN CATALYST SYSTEMS | WACKER-CHEMIE GMBH (DE) | 1999-12-28 | — | — | US | disclosed |
| CN-1198170-A | Mesoscopic organopolysiloxane particles with chemically bonded metal compounds | WACKER CHEMIE GMBH (DE) | 1998-11-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | SFN, FANCF, B2M | HTR2A 2488/4885GPR3 2696/4885DRD2 798/4885 |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | PYM1, SFN, FANCF | HTR2A 2852/4885GPR3 3611/4885DRD2 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.