Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.42 |
| ▸ | DRD4 | P21917 | 10/20 | 0.42 |
| ▸ | DRD3 | P35462 | 10/20 | 0.42 |
| ▸ | HTR2A | P28223 | 9/20 | 0.42 |
| ▸ | DRD1 | P21728 | 8/20 | 0.42 |
| ▸ | DRD5 | P21918 | 4/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31383667 | 0.88 | DRD2 (0.43) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL31383668 | 0.76 | RET (0.35) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL23087424 | 0.75 | DRD2 (0.46) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL31030378 | 0.73 | DRD2 (0.47) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL31487829 | 0.72 | MAPK14 (0.49) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3616028 | 0.71 | DRD2 (0.51) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3073748 | 0.70 | SCN5A (0.46) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL5481920 | 0.69 | TDP1 (0.62) | DRD2DRD4ALDH1A1TP53CYP3A4 | |
| SCHEMBL4278181 | 0.68 | TP53 (0.50) | DRD2DRD4GRM5ALDH1A1TP53 | |
| SCHEMBL22290928 | 0.68 | ALDH1A1 (0.50) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051363-A1 | Substituted Pyrazolopyridines | NEURO3 THERAPEUTICS INC (US) | 2025-02-13 | — | — | US | disclosed |
| WO-2025029897-A1 | SUBSTITUTED PYRAZOLOPYRIDINES | NEURO3 THERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051363-A1 | Substituted Pyrazolopyridines | QDPR, DPYD, P2RX4 | DRD2 2058/4885DRD4 1232/4885DRD3 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.