Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306113 | 0.97 | — | — | |
| SCHEMBL29421562 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL28164484 | 0.95 | ALDH1A1 (0.40) | ALDH1A1ACHEMAPTNPC1RAB9A | |
| Fluoride SCHEMBL27656662 | 0.95 | ALDH1A1 (0.40) | ALDH1A1ACHEMAPTNPC1RAB9A | |
| Cyanide SCHEMBL28824673 | 0.91 | ALDH1A1 (0.37) | ALDH1A1ACHEMAPTNPC1RAB9A | |
| Formic Acid SCHEMBL28032861 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL1492581 | 0.80 | ALDH1A1 (0.40) | ALDH1A1ACHEMAPTNPC1RAB9A | |
| SCHEMBL22778153 | 0.79 | TNKS2 (0.43) | ALDH1A1ACHEMAPTNPC1RAB9A | |
| SCHEMBL29468034 | 0.79 | TNKS2 (0.43) | ALDH1A1ACHEMAPTNPC1RAB9A | |
| SCHEMBL257139 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117976986-A | Fluorine-containing rechargeable magnesium battery electrolyte and preparation method and application thereof | 重庆大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-112955436-B | 6-oxo-1, 6-dihydropyridazine derivatives, preparation method and application thereof in medicines | 福建盛迪医药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-110177554-B | Combination therapy for the treatment of cancer | G1治疗公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-112996774-B | 2-oxo-1,2-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-108699024-B | Benzothienyl selective estrogen receptor down-regulator compounds | 伊利诺伊大学评议会 | 2022-03-11 | — | — | CN | disclosed |
| CN-108495628-B | Benzothienyl selective estrogen receptor down-modulators | 伊利诺伊大学评议会 | 2022-01-11 | — | — | CN | disclosed |
| CN-112996774-A | 2-oxo-1, 2-dihydropyridine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112955436-A | 6-oxo-1, 6-dihydropyridazine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-10858366-B2 | Tricyclic compounds useful to treat orthomyxovirus infections | NOVARTIS AG (CH) | 2020-12-08 | — | — | US | disclosed |
| WO-2020140959-A1 | 6-OXO-1,6-DIHYDROPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2020-07-09 | — | — | WO | disclosed |
| EP-1326832-B1 | CHEMICAL COMPOUNDS | GLAXO GROUP LTD (GB) | 2004-10-06 | — | — | EP | disclosed |
| US-20040127485-A1 | 1,4! - diazepane -1- carboxylic acid derivatives process for their preparation and their use as tachykinin antagonists | GLAXO GROUP LIMITED (GB) | 2004-07-01 | — | — | US | disclosed |
| US-20040014770-A1 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 2004-01-22 | — | — | US | disclosed |
| EP-1377558-A1 | [1,4]-DIAZEPANE-1-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-01-07 | — | — | EP | disclosed |
| WO-2003066635-A1 | PIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003066621-A1 | PIPERIDINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF TACHYKININS | GLAXO GROUP LIMITED (GB) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003066589-A1 | PIPERIDYLCARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF TACHYKINIM-MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-08-14 | — | — | WO | disclosed |
| EP-1326832-A1 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002081457-A1 | `1,4!-DIAZEPANE-1-CARBOXYLIC ACID DERIVATIVES PROCESS FOR THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002032867-A1 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858366-B2 | Tricyclic compounds useful to treat orthomyxovirus infections | ZC3HAV1, OTC, THOP1 | ALDH1A1 4445/4885ACHE 320/4885MAPT 797/4885 |
| US-20040127485-A1 | 1,4! - diazepane -1- carboxylic acid derivatives process for their preparation and their use as tachykinin antagonists | NPY1R, CRHR1, GRIN1 | ALDH1A1 2441/4885ACHE 2007/4885MAPT 3460/4885 |
| US-20040014770-A1 | Chemical compounds | HCK, KCNK4, GRK4 | ALDH1A1 2296/4885ACHE 2734/4885MAPT 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.