Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CD69 | Q07108 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31383943 | 0.79 | SLC6A2 (0.38) | KMT2APKMTSHRHSD17B10MEN1 | |
| SCHEMBL16672851 | 0.74 | FFAR1 (0.49) | ALOX15KMT2APOLBSMN1; SMN2GLA | |
| SCHEMBL26629385 | 0.72 | ADRA1D (0.36) | POLBALDH1A1PKMTSHRTHRA | |
| SCHEMBL9646424 | 0.68 | KMT2A (0.66) | LMNAALOX15KMT2ACD69POLB | |
| SCHEMBL9292031 | 0.68 | KDM4E (0.39) | LMNAALOX15KMT2ACD69POLB | |
| SCHEMBL29876470 | 0.68 | KDM4E (0.41) | POLBSMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL29143120 | 0.68 | KDM4E (0.41) | POLBSMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL29143124 | 0.68 | KDM4E (0.41) | POLBSMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL24488931 | 0.68 | KMT2A (0.46) | LMNAALOX15KMT2APOLBGLA | |
| SCHEMBL22945646 | 0.68 | KMT2A (0.46) | LMNAALOX15KMT2APOLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064802-A1 | INHIBITING HUMAN INTEGRIN α5β1 | MORPHIC THERAPEUTIC, INC. (US) | 2025-03-27 | — | — | WO | disclosed |