Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.78 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.78 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.78 |
| ▸ | AHCY | P23526 | 6/20 | 0.76 |
| ▸ | NADK | O95544 | 1/20 | 0.74 |
| ▸ | PNMT | P11086 | 1/20 | 0.74 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.74 |
| ▸ | SRM | P19623 | 3/20 | 0.72 |
| ▸ | SMS | P52788 | 1/20 | 0.72 |
| ▸ | DPP4 | P27487 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylthioadenosine SCHEMBL29361072 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL29439558 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL101382 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL31388809 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL160358 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL890628 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL10013421 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL11954365 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| Methylthioadenosine SCHEMBL20798030 | 0.95 | AHCY (0.83) | DOT1LDNMT3BPRMT7AHCYNADK | |
| SCHEMBL10665713 | 0.88 | DOT1L (1.00) | DOT1LDNMT3BPRMT7AHCYNADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030224472-A1 | Methods for the identification of inhibitors of putrescine aminopropyltransferase as antibiotics | ICORIA, INC. | 2003-12-04 | — | — | US | disclosed |