Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 12/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388902 | 0.81 | NOTCH1 (0.48) | MAPTP2RY14GPR119RORCTACR1 | |
| SCHEMBL31388944 | 0.80 | GPR119 (0.54) | GPR119HRH3 | |
| SCHEMBL31388952 | 0.79 | RORC (0.45) | GPR119RORCTACR1HRH3 | |
| SCHEMBL2297690 | 0.78 | P2RY14 (0.64) | MAPTP2RY14GPR119RORCSTS | |
| SCHEMBL23859749 | 0.78 | MGLL (0.56) | MAPTP2RY14GPR119RORCTACR1 | |
| SCHEMBL29427054 | 0.78 | MGLL (0.56) | MAPTP2RY14GPR119RORCTACR1 | |
| SCHEMBL5557626 | 0.78 | SLC6A9 (0.53) | MAPTP2RY14GPR119 | |
| SCHEMBL22059421 | 0.76 | RORC (0.57) | MAPTP2RY14GPR119RORCTACR1 | |
| SCHEMBL21425200 | 0.75 | MAPT (0.56) | MAPTP2RY14GPR119RORCTACR1 | |
| SCHEMBL6795066 | 0.75 | MAPT (0.55) | MAPTGPR119RORCTACR1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362153-B | Azaspiro compounds as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-01-07 | — | — | CN | disclosed |