Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.45 |
| ▸ | BCL2 | P10415 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389274 | 0.90 | ALOX15 (0.55) | ALOX15KDM4ELMNAHPGDMCL1 | |
| SCHEMBL31389291 | 0.81 | ALOX15 (0.51) | ALOX15KDM4EHPGDP2RY12TDP1 | |
| SCHEMBL90018 | 0.80 | ALOX15 (0.53) | ALOX15KDM4EHPGDP2RY12PLA2G2A | |
| SCHEMBL31389258 | 0.79 | ALOX15 (0.52) | ALOX15KDM4EP2RY12PLA2G2A | |
| SCHEMBL9379922 | 0.79 | ALOX15 (0.52) | ALOX15KDM4EP2RY12PLA2G2A | |
| SCHEMBL31389238 | 0.79 | ALOX15 (0.57) | ALOX15KDM4ELMNAP2RY12PLA2G2A | |
| SCHEMBL9381350 | 0.77 | ALOX15 (0.55) | ALOX15KDM4EP2RY12 | |
| SCHEMBL31389266 | 0.77 | ALOX15 (0.55) | ALOX15LMNAHPGDTDP1 | |
| SCHEMBL31389236 | 0.76 | MAPT (0.58) | ALOX15KDM4ELMNATDP1L3MBTL1 | |
| SCHEMBL31389251 | 0.76 | ALOX15 (0.77) | ALOX15KDM4ELMNAHPGDP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |