Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090515 | 0.90 | PLA2G2A (0.47) | ALOX15KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL31389263 | 0.87 | ALOX15 (0.59) | ALOX15KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL90018 | 0.85 | ALOX15 (0.53) | ALOX15KDM4EALDH1A1HPGDNCF1 | |
| SCHEMBL31389269 | 0.84 | ALOX15 (0.50) | ALOX15TDP1KMT2AMAPT | |
| SCHEMBL31389258 | 0.84 | ALOX15 (0.52) | ALOX15KDM4ENCF1P2RY12 | |
| SCHEMBL9379922 | 0.84 | ALOX15 (0.52) | ALOX15KDM4EALDH1A1KMT2ANCF1 | |
| SCHEMBL31389238 | 0.83 | ALOX15 (0.57) | ALOX15KDM4EP2RY12 | |
| SCHEMBL31389266 | 0.81 | ALOX15 (0.55) | ALOX15ALDH1A1HPGDTDP1MAPT | |
| SCHEMBL9381350 | 0.81 | ALOX15 (0.55) | ALOX15KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL31389287 | 0.81 | ALOX15 (0.46) | ALOX15KDM4EHPGDTDP1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |