Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407292 | 0.85 | THRB (0.32) | TSHR | |
| SCHEMBL5391855 | 0.84 | LMNA (0.38) | TSHR | |
| SCHEMBL5399382 | 0.83 | ADA (0.33) | TSHR | |
| Bromide SCHEMBL5387970 | 0.82 | LMNA (0.37) | TSHR | |
| SCHEMBL5390248 | 0.82 | ADORA2A (0.36) | TSHR | |
| SCHEMBL5386625 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL5389139 | 0.81 | TSHR (0.30) | TSHR | |
| Bromide SCHEMBL5386504 | 0.81 | ADORA2A (0.36) | TSHR | |
| SCHEMBL5382982 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL3943493 | 0.81 | TSHR (0.34) | TSHRGRIA1GRIA2GRIA4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025395-A1 | Means for Oxidatively Dyeing Keratin Fibers | HENKEL AG & CO. KGAA (DE) | 2025-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025395-A1 | Means for Oxidatively Dyeing Keratin Fibers | KRT18, SQOR, ADH4 | TSHR 4573/4885GRIA1 3128/4885GRIA2 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.