Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389249 | 1.00 | ALOX15 (0.47) | ALOX15MAPTTDP1MAOBTP53 | |
| SCHEMBL31389266 | 0.90 | ALOX15 (0.55) | ALOX15MAPTTDP1TP53ADAM17 | |
| SCHEMBL31389289 | 0.89 | MAPT (0.58) | ALOX15MAPTTDP1TP53ADAM17 | |
| SCHEMBL31389242 | 0.89 | ALOX15 (0.54) | ALOX15MAOBPTGER1CYP1A2MRGPRX4 | |
| SCHEMBL20877162 | 0.88 | TP53 (0.47) | MAPTTP53PTGER1CYP1A2 | |
| SCHEMBL17769171 | 0.86 | LMNA (0.50) | MAPTTP53PTGER1CYP1A2ALDH1A1 | |
| SCHEMBL31389256 | 0.83 | ALOX15 (0.50) | ALOX15MAPTTDP1TP53ADAM17 | |
| SCHEMBL31389265 | 0.82 | MAPT (0.50) | ALOX15MAPTTDP1TP53ADAM17 | |
| SCHEMBL31389236 | 0.82 | MAPT (0.58) | ALOX15MAPTTDP1TP53GAA | |
| SCHEMBL31389296 | 0.82 | ALOX15 (0.52) | ALOX15MAPTTDP1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |