Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389907 | 0.78 | ATM (0.38) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31389485 | 0.76 | POLB (0.58) | ALDH1A1MAPTPOLBPDE4BPDE4D | |
| SCHEMBL31389617 | 0.75 | TBXAS1 (0.42) | ELANEPDE4BPDE4D | |
| SCHEMBL31389550 | 0.70 | POLB (0.37) | KMT2AMAPTPOLBLRRK2 | |
| SCHEMBL30509491 | 0.70 | KDM4E (0.46) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3635584 | 0.70 | KDM4E (0.40) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31389636 | 0.68 | POLB (0.36) | MAPTPOLBLRRK2 | |
| SCHEMBL31389620 | 0.67 | KDM4E (0.47) | KDM4ERETKDRPDE4BPDE4D | |
| SCHEMBL1772375 | 0.65 | KDM4E (0.40) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31389987 | 0.64 | LRRK2 (0.43) | MEN1KMT2AALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |