Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389738 | 0.79 | HTR3A (0.36) | POLBMAPTTP53 | |
| SCHEMBL31389485 | 0.79 | POLB (0.58) | POLBMAPTTP53 | |
| SCHEMBL31389550 | 0.79 | POLB (0.37) | POLBMAPTLRRK2TP53 | |
| SCHEMBL31389453 | 0.68 | KDM4E (0.39) | POLBMAPTLRRK2 | |
| SCHEMBL31389849 | 0.68 | RPS6KA5 (0.38) | POLB | |
| SCHEMBL31389471 | 0.68 | CYP11B2 (0.36) | POLBLRRK2 | |
| SCHEMBL31389529 | 0.68 | CCR5 (0.47) | MAPTTP53 | |
| SCHEMBL31389433 | 0.67 | SPR (0.32) | LRRK2 | |
| SCHEMBL31389934 | 0.67 | — | — | |
| SCHEMBL31389454 | 0.56 | PDE10A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |