SCHEMBL31389490

SCHEMBL31389490

CC1c2cc(CO)nn2CCN1C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.37
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31389640 0.78 RIPK1 (0.34) GRM5
SCHEMBL30756315 0.75 MAOA (0.31) MAOA
SCHEMBL14926131 0.75 MAOA (0.31) MAOA
SCHEMBL31389700 0.74
SCHEMBL31389725 0.73 RIPK1 (0.37)
SCHEMBL31389754 0.73
SCHEMBL23801586 0.72 LRRK2 (0.32)
SCHEMBL28627562 0.69
SCHEMBL28626574 0.69
SCHEMBL31389667 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043225-A2 DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 GENENTECH, INC. (US) 2025-02-27 WO disclosed