SCHEMBL31389640

SCHEMBL31389640

CC1CCn2nc(CO)cc21

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.34
GRM5 P41594 2/20 0.34
DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31389700 0.92
SCHEMBL31389490 0.78 GRM5 (0.37) GRM5
SCHEMBL31389754 0.77
SCHEMBL31389725 0.77 RIPK1 (0.37) RIPK1
SCHEMBL28627562 0.76
SCHEMBL31389530 0.75 DRD4 (0.33) GRM5DRD4
SCHEMBL31389667 0.74
SCHEMBL31511159 0.74 NOS3 (0.33) RIPK1
SCHEMBL31389779 0.72 RIPK1 (0.47) RIPK1GRM5
SCHEMBL20645944 0.72 RIPK1 (0.64) RIPK1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043225-A2 DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 GENENTECH, INC. (US) 2025-02-27 WO disclosed