Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397402 | 0.89 | PDK1 (0.48) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL12922693 | 0.79 | PARP1 (0.53) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL8005977 | 0.79 | PARP1 (0.50) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL31389830 | 0.78 | PDK1 (0.38) | ALDH1A1GAASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL31389752 | 0.77 | FABP4 (0.41) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL31389958 | 0.73 | KDM4E (0.38) | ALDH1A1GAALMNASMN1; SMN2HTT | |
| SCHEMBL31389424 | 0.73 | KDM4E (0.50) | ALDH1A1GAALMNASMN1; SMN2PDK1 | |
| SCHEMBL1855201 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL977531 | 0.71 | ADORA1 (0.52) | ALDH1A1GAASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL2759857 | 0.71 | PDK1 (0.46) | ALDH1A1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |