Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392722 | 0.76 | ADORA2B (0.51) | ADORA2BADORA3ALDH1A1CNOT7BLM | |
| SCHEMBL10696644 | 0.73 | ADORA2B (0.65) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL10696881 | 0.72 | CNOT7 (0.53) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL8355196 | 0.71 | CYP3A4 (0.64) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL11873472 | 0.70 | ADORA2B (0.59) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL31392715 | 0.69 | GRIN1 (0.42) | MEN1KMT2ABRD4CNOT7POLB | |
| SCHEMBL5174205 | 0.69 | ADORA2B (0.51) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL31392676 | 0.69 | GRIN1 (0.50) | ADORA2BADORA3CNOT7MAPT | |
| SCHEMBL26925735 | 0.69 | CYP3A4 (0.66) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL10696008 | 0.69 | ADORA2B (0.46) | PDE4AADORA2APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533607-B | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2025-01-07 | — | — | CN | disclosed |