Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 4/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392747 | 0.83 | NOTUM (0.40) | NOTUMRAB9AIDO1TSHRMAPK1 | |
| SCHEMBL31392753 | 0.83 | NOTUM (0.47) | NOTUMALDH1A1HTTCCR9 | |
| SCHEMBL31392717 | 0.80 | NOTUM (0.39) | NOTUM | |
| SCHEMBL31392746 | 0.80 | NOTUM (0.44) | NOTUMRAB9AALDH1A1CCR9 | |
| SCHEMBL31392762 | 0.78 | NOTUM (0.42) | NOTUMRAB9ATSHRMAPK1ALDH1A1 | |
| SCHEMBL31392721 | 0.78 | NOTUM (0.39) | NOTUM | |
| SCHEMBL2925335 | 0.76 | PTGS2 (0.56) | NOTUMRAB9ANPC1PTGS2CCR2 | |
| SCHEMBL31392807 | 0.75 | NOTUM (0.46) | NOTUMALDH1A1 | |
| SCHEMBL13628824 | 0.75 | RAB9A (0.36) | NOTUMRAB9ANPC1PTGS2TSHR | |
| SCHEMBL31392808 | 0.74 | LMNA (0.42) | NOTUMRAB9ANPC1IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350315-A | 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof | 南开大学 | 2025-01-24 | — | — | CN | claimed |
| CN-119350315-A | 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof | 南开大学 | 2025-01-24 | — | — | CN | disclosed |