Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP5 | Q16690 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 5/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722008 | 0.98 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| Potassium Ion SCHEMBL3222667 | 0.96 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| Tiron SCHEMBL29385574 | 0.96 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| SCHEMBL9328871 | 0.96 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| Tiron SCHEMBL22220 | 0.96 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| SCHEMBL5310574 | 0.96 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| SCHEMBL8717950 | 0.96 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| Water SCHEMBL5097417 | 0.94 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| Water SCHEMBL3205313 | 0.94 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PTGS1PKLR | |
| Ammonia Solution, Strong SCHEMBL9751555 | 0.94 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PTGS1PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109877-A1 | HEPARAN SULFATE REPLACEMENT THERAPY | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2011-09-15 | — | — | WO | claimed |
| US-20120058166-A1 | FILAMENTS COMPRISING A NON-PERFUME ACTIVE AGENT NONWOVEN WEBS AND METHODS FOR MAKING SAME | GLENN JR ROBERT WAYNE (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120048769-A1 | PROCESS FOR MAKING FILMS FROM NONWOVEN WEBS | SIVIK MARK ROBERT (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120052036-A1 | FILAMENTS COMPRISING AN ACTIVE AGENT NONWOVEN WEBS AND METHODS FOR MAKING SAME | GLENN JR ROBERT WAYNE (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053108-A1 | METHOD FOR DELIVERING AN ACTIVE AGENT | GLENN JR ROBERT WAYNE (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2011109877-A1 | HEPARAN SULFATE REPLACEMENT THERAPY | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2011-09-15 | — | — | WO | disclosed |
| US-5320969-A | Measuring the change in color when complexing a metal compound and colored indicator in a buffered solution of biological sample, e.g. urine | MILES INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5302531-A | Mixture of complexing agent, metal compound and indicator | MILES INC. (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0397213-A1 | Radiolabeled antibody fragments | MALLINCKRODT, INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| EP-0350972-A2 | Radiolabeled antibody fragments | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1990-01-17 | — | — | EP | disclosed |
| EP-0178125-A2 | Labeled antibody fragments. | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052036-A1 | FILAMENTS COMPRISING AN ACTIVE AGENT NONWOVEN WEBS AND METHODS FOR MAKING SAME | VCL, KRT18, TPM4 | DUSP5 3062/4885PTPN1 3368/4885DUSP6 2559/4885 |
| US-20120058166-A1 | FILAMENTS COMPRISING A NON-PERFUME ACTIVE AGENT NONWOVEN WEBS AND METHODS FOR MAKING SAME | KRT18, FLNA, NEFM | DUSP5 2418/4885PTPN1 1574/4885DUSP6 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.