Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR known ✓ | P30613 | 5/20 | 0.44 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.41 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.39 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.36 |
| ▸ | DUSP5 | Q16690 | 4/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.55 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL29379961 | 1.00 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Water SCHEMBL5097417 | 1.00 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Tiron SCHEMBL29385574 | 0.98 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL5310574 | 0.98 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Tiron SCHEMBL22220 | 0.98 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL10722008 | 0.96 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Ammonia Solution, Strong SCHEMBL9751555 | 0.96 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Water SCHEMBL9466386 | 0.96 | DUSP5 (0.58) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL9328871 | 0.94 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL31393 | 0.94 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PKLRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076841-B1 | BONDED ABRASIVE ARTICLE AND METHOD OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-01-31 | — | — | EP | claimed |
| US-20230001543-A1 | BONDED ABRASIVE ARTICLE AND METHOD OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2023-01-05 | — | — | US | claimed |
| EP-4076841-A1 | BONDED ABRASIVE ARTICLE AND METHOD OF MAKING THE SAME | 3M Innovative Properties Company (US) | 2022-10-26 | — | — | EP | claimed |
| US-20220186059-A1 | INK COMPOSITION INCLUDING A MODIFIED FATTY ALCOHOL POLYGLYCOL ETHER SURFACTANT | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2022-06-16 | — | — | US | claimed |
| CN-111433298-B | Dye sublimation ink thermal inkjet printing method | 惠普发展公司，有限责任合伙企业 | 2022-06-07 | — | — | CN | claimed |
| US-11235587-B2 | Inkjet pre-treatment fluid for dye sublimation printing | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2022-02-01 | — | — | US | claimed |
| WO-2021124059-A1 | BONDED ABRASIVE ARTICLE AND METHOD OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-06-24 | — | — | WO | claimed |
| EP-0682289-B1 | Photographic color-developing chemicals in the form of granules | KONISHIROKU PHOTO IND (JP) | 1999-02-03 | — | — | EP | claimed |
| US-20260145381-A1 | THREE-DIMENSIONAL PRINTING WITH PHOTOBLEACHABLE DYE(S) | PERIDOT PRINT LLC (US) | 2026-05-28 | — | — | US | disclosed |
| US-20260146170-A1 | THREE-DIMENSIONALLY PRINTED PARTS AND SECOND-GENERATION PRODUCTS FORMED THEREFROM | PERIDOT PRINT LLC (US) | 2026-05-28 | — | — | US | disclosed |
| US-20260145380-A1 | THREE-DIMENSIONAL PRINTING WITH VISIBLE LIGHT ABSORBING PIGMENTS | PERIDOT PRINT LLC (US) | 2026-05-28 | — | — | US | disclosed |
| US-20260146175-A1 | THREE-DIMENSIONAL PRINTING WITH VISIBLE LIGHT ABSORBING DYES | PERIDOT PRINT LLC (US) | 2026-05-28 | — | — | US | disclosed |
| US-20260146173-A1 | THREE-DIMENSIONAL PRINTING WITH COLOR ASSIST AGENT | PERIDOT PRINT LLC (US) | 2026-05-28 | — | — | US | disclosed |
| US-12616197-B2 | Three-dimensional printing | PERIDOT PRINT LLC (US) | 2026-05-05 | — | — | US | disclosed |
| EP-0687951-B1 | Granular or tablet-form color-developing composition | KONISHIROKU PHOTO IND (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6287753-B1 | CONTROLLING PARTICLE SIZE | FUJI PHOTO FILM CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0678782-B1 | Method for manufacturing solid processing composition for silver halide photographic light-sensitive materials | KONISHIROKU PHOTO IND (JP) | 2001-02-14 | — | — | EP | disclosed |
| EP-0682289-B1 | Photographic color-developing chemicals in the form of granules | KONISHIROKU PHOTO IND (JP) | 1999-02-03 | — | — | EP | disclosed |
| EP-0678782-A1 | Method for manufacturing solid processing composition for silver halide photographic light-sensitive materials | KONICA CORPORATION (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5126475-A | Reaction of phosphorus halide with ammonium salt of water insoluble hydroxysulfonic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260146175-A1 | THREE-DIMENSIONAL PRINTING WITH VISIBLE LIGHT ABSORBING DYES | ADH1A, ADH1C, ADH5 | PKLR 644/4885PTGS1 499/4885MEN1 3211/4885 |
| US-20260145381-A1 | THREE-DIMENSIONAL PRINTING WITH PHOTOBLEACHABLE DYE(S) | RAB7A, FUS, FES | PKLR 686/4885PTGS1 3724/4885MEN1 4045/4885 |
| US-20260145380-A1 | THREE-DIMENSIONAL PRINTING WITH VISIBLE LIGHT ABSORBING PIGMENTS | ADH1A, ADH1C, ADH5 | PKLR 1678/4885PTGS1 562/4885MEN1 2527/4885 |
| US-20260146170-A1 | THREE-DIMENSIONALLY PRINTED PARTS AND SECOND-GENERATION PRODUCTS FORMED THEREFROM | NOTCH2, NOTCH3, HTR3D | PKLR 2502/4885PTGS1 2879/4885MEN1 3360/4885 |
| US-20260146173-A1 | THREE-DIMENSIONAL PRINTING WITH COLOR ASSIST AGENT | FUS, FES, WNT3A | PKLR 3620/4885PTGS1 4311/4885MEN1 3116/4885 |
| US-12616197-B2 | Three-dimensional printing | MYD88, MYB, HTR3D | PKLR 2012/4885PTGS1 2133/4885MEN1 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.