Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tiron. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.42 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.36 |
| ▸ | DUSP5 | Q16690 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.52 |
| ▸ | PKLR | P30613 | 5/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tiron SCHEMBL29385574 | 1.00 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL5310574 | 1.00 | DUSP5 (0.65) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Water SCHEMBL5097417 | 0.98 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Water SCHEMBL29379961 | 0.98 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Water SCHEMBL3205313 | 0.98 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL10722008 | 0.98 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Ammonia Solution, Strong SCHEMBL9751555 | 0.98 | DUSP5 (0.62) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL31393 | 0.96 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| Potassium Ion SCHEMBL3222667 | 0.96 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PKLRPTGS1 | |
| SCHEMBL9328871 | 0.96 | DUSP5 (0.59) | DUSP5PTPN1DUSP6PKLRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6575 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090621-A1 | SYSTEMS, DEVICES, AND METHODS FOR SEPARATION OF METALS FROM WASTE, SCRAP, AND POST-CONSUMER PRODUCTS | SUNCHEM INC. (US) | 2026-04-30 | — | — | WO | claimed |
| EP-3301162-B1 | LOW PH LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2026-04-15 | — | — | EP | claimed |
| EP-3301163-B1 | LOW PH LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2026-04-15 | — | — | EP | claimed |
| EP-3301164-B1 | LOW PH LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2026-04-15 | — | — | EP | claimed |
| EP-4206645-B1 | METHOD AND APPARATUS FOR REMOVING OR REDUCING FORMATION OF PRECIPITATES GENERATED IN HEMATOXYLIN SOLUTIONS | VENTANA MED SYST INC (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4699720-A2 | FOUNDRY SLIP | Safran (FR) | 2026-02-25 | — | — | EP | claimed |
| EP-3684525-B1 | USE OF A CASTING SLURRY | SAFRAN (FR) | 2026-02-18 | — | — | EP | claimed |
| US-12533430-B2 | Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof | Chengdu New Radiomedicine Technology Co., Ltd. (CN) | 2026-01-27 | — | — | US | claimed |
| EP-4665689-A1 | ANTISCALANT COMPOSITIONS AND METHODS OF USE | Locus Solutions IPCO, LLC (US) | 2025-12-24 | — | — | EP | claimed |
| EP-3301151-B1 | LOW PH LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2025-11-12 | — | — | EP | claimed |
| US-5302531-A | Mixture of complexing agent, metal compound and indicator | MILES INC. (US) | 1994-04-12 | — | — | US | claimed |
| WO-1994001142-A1 | THERAPEUTIC COMPOSITIONS AND METHODS USING PQQ | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1994-01-20 | — | — | WO | claimed |
| US-5242832-A | Surfactants and hemoglobin stabilizers | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1993-09-07 | — | — | US | claimed |
| WO-1993014751-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AS ACTIVE PRINCIPLE ASSOCIATIONS OF VANADIUM AND/OR NIOBIUM WITH PYROCATECHOL DERIVATIVES | I.R.2.M. (FR) | 1993-08-05 | — | — | WO | claimed |
| EP-0444241-A1 | Reagent for measurement of leukocytes and hemoglobin in blood | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1991-09-04 | — | — | EP | claimed |
| US-4714614-A | PSEUDOMONAS AND FERRIC ION CHELATING AGENT | COLORADO STATE UNIVERSITY (US) | 1987-12-22 | — | — | US | claimed |
| US-4279870-A | Liquid-liquid extraction process for the recovery of tungsten from low level sources | GTE LABORATORIES INCORPORATED (US) | 1981-07-21 | — | — | US | claimed |
| US-4264716-A | STABILIZED BY ADDITION OF AN AMINOPOLYPHOSPHONIC ACID SEQUESTERING AGENT | EASTMAN KODAK COMPANY (US) | 1981-04-28 | — | — | US | claimed |
| US-4194954-A | Electrolytic etch preparation of semiconductor surfaces | THE POST OFFICE (GB) | 1980-03-25 | — | — | US | claimed |
| US-4112044-A | CATALYTIC | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1978-09-05 | — | — | US | claimed |