Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398697 | 0.84 | RXRA (0.69) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL29129667 | 0.83 | AR (0.56) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL25304603 | 0.81 | CYP3A4 (0.55) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL17949776 | 0.79 | RXRA (0.72) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL17716251 | 0.79 | POLH (0.56) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL620145 | 0.79 | MAPT (0.64) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL31670262 | 0.79 | MAPT (0.64) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL15920417 | 0.78 | POLH (0.58) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL16688554 | 0.77 | POLH (0.60) | ARCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL2274000 | 0.77 | MAOA (0.41) | CYP3A4MAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569692-A | Xanthohumol derivative in hops, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-03-07 | — | — | CN | claimed |
| CN-119569692-A | Xanthohumol derivative in hops, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-03-07 | — | — | CN | disclosed |