Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357424 | 0.84 | RIPK1 (0.50) | RIPK1TSHRCA1CA2CA7 | |
| SCHEMBL2022537 | 0.77 | SIGMAR1 (0.45) | RIPK1KDM4EALOX15HSD17B10MAPT | |
| SCHEMBL753626 | 0.77 | SIGMAR1 (0.45) | RIPK1KDM4EALOX15HSD17B10MAPT | |
| SCHEMBL5912567 | 0.75 | ALDH1A1 (0.47) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL28502700 | 0.74 | RIPK1 (0.47) | RIPK1TSHRKDM4EALOX15HTT | |
| SCHEMBL27883671 | 0.73 | RIPK1 (0.51) | RIPK1TSHRKDM4EALOX15HTT | |
| SCHEMBL28031012 | 0.73 | RIPK1 (0.51) | RIPK1TSHRKDM4EALOX15HTT | |
| SCHEMBL6528998 | 0.73 | RIPK1 (0.59) | RIPK1CA7KDM4EALOX15HTT | |
| SCHEMBL28500347 | 0.72 | RIPK1 (0.47) | RIPK1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL27789415 | 0.72 | PTPN1 (0.44) | RIPK1HTTALDH1A1CYP1A2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569692-A | Xanthohumol derivative in hops, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-03-07 | — | — | CN | claimed |
| CN-119569692-A | Xanthohumol derivative in hops, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-03-07 | — | — | CN | disclosed |