Phelligridin J

Phelligridin J

SCHEMBL31399403

O=C(O)c1cc2oc(=O)c3cc(O)c(O)cc3c2c(=O)o1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKLR P30613 3/20 0.45
NT5E P21589 4/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
KDM4E B2RXH2 5/20 0.43
RECQL P46063 4/20 0.43
BLM P54132 4/20 0.43
MAPT P10636 4/20 0.43
GAA P10253 3/20 0.43
HPGD P15428 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALPI P09923 1/20 0.43
PKM P14618 1/20 0.43
CASP3 P42574 1/20 0.43
CASP7 P55210 1/20 0.43
CASP6 P55212 1/20 0.43
MCL1 Q07820 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
THRB P10828 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319353 0.76 BCL2L1 (0.46) PKLRNT5EMEN1KMT2AKDM4E
SCHEMBL5563883 0.69 AKR1B1 (0.65) KDM4EMAPTHPGDCYP3A4HSD17B10
SCHEMBL7983695 0.69 PKLR (0.69) PKLRNT5EMEN1KMT2AKDM4E
SCHEMBL13064967 0.68 KDM4E (0.46) PKLRNT5EMEN1KMT2AKDM4E
Phelligridin D SCHEMBL29635990 0.67 NT5E (0.86) PKLRNT5EMEN1KMT2AKDM4E
Phelligridin C SCHEMBL29992860 0.67 NT5E (0.71) PKLRNT5EMEN1KMT2AKDM4E
Phelligridin D SCHEMBL17394787 0.67 NT5E (0.86) PKLRNT5EMEN1KMT2AKDM4E
SCHEMBL29127652 0.65 PIM1 (0.54) KMT2AKDM4EMAPTHPGDHSD17B10
Demethylwedelolactone SCHEMBL3364302 0.64 MEN1 (0.72) PKLRMEN1KMT2AKDM4ERECQL
Demethylwedelolactone SCHEMBL31146849 0.64 MEN1 (0.72) PKLRMEN1KMT2AKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119524031-A Preparation of Phellinus linteus extract and application of Phellinus linteus extract in improving and/or treating myocardial infarction products 瑞安市人民医院(瑞安市人民医院医疗服务集团瑞安市红十字医院) 2025-02-28 CN disclosed